Houston Astros at Chicago White Sox, 7:35PM
Roger Clemens (13-8, 1.87 ERA) vs Jose Contreras (15-7, 3.61 ERA)
Both teams rely on their pitching to win games. The White Sox have more players in their lineup that can go deep, which is a good way to beat good pitching. I'd give the advantage to the Houston bullpen, but that's assuming Chicago actually uses their pen.